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GENOMICS AND BIOINFORMATICS GRAZ
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GENERAL DESCRIPTION

Data analysis of state of the art genomic scale microarrays gets more and more impractical or even impossible to perform on commonly used workstations due to the vast amount of data. CPU performance, amount of memory and costs are the limiting factors. Therefore memory and calculation intensive tasks have to be outsourced to high performance servers with a sufficient amount of memory.

Genesis Server is an application server for computation of Hierarchical Clustering, Self Organizing Maps (SOM), k-means Clustering and Support Vector Machines (SVM).

         
Data analysis is prepared in our well established Genesis Client and the jobs are distributed to an available server, where the calculation is started and results are stored until they are fetched by the client. At all times the client is informed about status and progress of the calculation task. Nevertheless all server jobs are completely independent from the client, so the client may be turned off during calculation and restarted again later to get the computed results


CITATION

Sturn A, Mlecnik B, Pieler R, Rainer J, Truskaller T, Trajanoski Z. Client-Server environment for high-performance gene expression data analysis. Bioinformatics. 19: 772-773 (2003) PM:12691990
Sturn A, Quackenbush J, Trajanoski Z. Genesis: cluster analysis of microarray data . Bioinformatics. 18: 207-208 (2002) PM:11836235
 
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