Data Adjustment: Percentage Cutoff

Parameter Information


Overview of Percentage Cutoff

The Percentage Cutoff data adjustment acts as a filter to remove genes that have fewer than some percentage of valid values for the experiments under study. It is common in microarray expression analysis to have some missing data, however, if a particular gene has fewer than some percentage of it's values then the gene can not be reliably compared to other genes.

This filtering method permits the you to select a criteria such that any gene having fewer good values than the supplied percentage will be removed from analyis runs. The history log will report the number of genes that are remaining after the cuttof is applied using the "use percent cutoff" menu option to enforce the cutoff.

Cutoff Parameter

This value, ranging from 0.0% to 100.0%, represents the percentage of valid values that a gene is required to have in order to be allowed into analysis algorithms. (e.g. 10 experiments loaded, cutoff criteria is 75%, if a gene has only 6 valid values (60%) then that gene is not a candidate for analysis while a gene having 8 valid values (80%) would be accepted.)